The PTSH Antibody (PAC050394) is a Polyclonal Antibody designed for research involving PTSH, a protein involved in thyroid function and regulation. The antibody, raised in rabbits, is highly reactive with human samples and is validated for use in various applications such as immunofluorescence, immunohistochemistry, and Western blotting. It binds specifically to the PTSH protein, enabling accurate detection and analysis in different cell types and tissues.PTSH, also known as prolyl-tRNA synthetase-associated protein, plays a crucial role in thyroid hormone synthesis and secretion, making it a key player in thyroid function and metabolism regulation.
Its involvement in these processes makes it a valuable target for research into thyroid disorders, metabolic diseases, and endocrine system dysregulation. Understanding the function and activity of PTSH is essential for developing new therapies and treatments for conditions related to thyroid and metabolic health.
Antibody Name:
ptsH Antibody (PACO50394)
Antibody SKU:
PACO50394
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:2000-1:10000
Species Reactivity:
Bacillus subtilis
Immunogen:
Recombinant Bacillus subtilis Phosphocarrier protein HPr protein (2-88AA)
Western Blot. Positive WB detected in Recombinant protein. All lanes: ptsH antibody at 2.8µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 26 kDa. Observed band size: 26 kDa..
Background:
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the permease (enzymes II/III).
Synonyms:
Phosphocarrier protein HPr (Histidine-containing protein), ptsH
UniProt Protein Function:
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the permease (enzymes II/III).
