PSG11 Polyclonal Antibody (PAC04206) is a high-quality research tool designed for the detection and analysis of PSG11, a key player in immune regulation and reproductive biology. This antibody, produced in rabbits, demonstrates strong reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the PSG11 protein, researchers can effectively study its expression and function in various cell types, making it a valuable tool for investigations in immunology and fertility research.PSG11, also known as pregnancy-specific glycoprotein 11, is involved in the modulation of immune responses during pregnancy and has been implicated in various reproductive processes.
Its role in immune tolerance and embryo implantation highlights its importance in understanding the mechanisms of successful pregnancy. Research into PSG11 may provide insights into infertility, miscarriages, and pregnancy complications, ultimately leading to the development of novel therapeutic strategies in reproductive medicine.Overall, the PSG11 Polyclonal Antibody offers researchers a reliable means to explore the intricate functions of PSG11 in both immune regulation and fertility, paving the way for advancements in reproductive health and reproductive biology.
Antibody Name:
PSG11 Antibody (PACO42406)
Antibody SKU:
PACO42406
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:2000
Species Reactivity:
Human
Immunogen:
Recombinant Human Pregnancy-specific beta-1-glycoprotein 11 protein (7-219AA)
Western blot. All lanes: PSG11 antibody at 12µg/ml + Hela whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 38, 24 kDa. Observed band size: 38 kDa.
PSG11: Belongs to the immunoglobulin superfamily. CEA family. 2 isoforms of the human protein are produced by alternative splicing
UniProt Protein Details:
Protein type:Secreted; Motility/polarity/chemotaxis; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 19q13.2
Cellular Component: extracellular region
Biological Process: female pregnancy
NCBI Summary:
The human pregnancy-specific glycoproteins (PSGs) are a group of molecules that are mainly produced by the placental syncytiotrophoblasts during pregnancy. PSGs comprise a subgroup of the carcinoembryonic antigen (CEA) family, which belongs to the immunoglobulin superfamily. For additional general information about the PSG gene family, see PSG1 (MIM 176390).[supplied by OMIM, Oct 2009]
