The PPP5C Polyclonal Antibody (PAC017372) is a valuable tool for researchers studying the PPP5C protein, a key regulator of cellular signaling pathways. This antibody, produced in rabbits, is highly specific for PPP5C in human samples and is optimized for Western blot applications. By targeting PPP5C, researchers can gain valuable insights into its role in various cellular processes, making it an essential tool for studies in molecular biology and cancer research.PPP5C, also known as serine/threonine-protein phosphatase 5, is involved in the regulation of protein phosphorylation and dephosphorylation, impacting diverse cellular functions such as signal transduction, cell cycle progression, and gene expression.
Dysregulation of PPP5C has been linked to cancer development, neurodegenerative diseases, and other pathological conditions, highlighting its significance as a therapeutic target. By using the PPP5C Polyclonal Antibody, researchers can explore the intricate mechanisms of PPP5C activity and its potential implications for disease management and treatment strategies.
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO17372(PPP5C Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200).
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: A375 cell and human fetal liver tissue, Primary antibody: PACO17372(PPP5C Antibody) at dilution 1/200 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds.
The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using PACO17372(PPP5C Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200).
Background:
This gene encodes a serine/threonine phosphatase which is a member of the protein phosphatase catalytic subunit family. Proteins in this family participate in pathways regulated by reversible phosphorylation at serine and threonine residues; many of these pathways are involved in the regulation of cell growth and differentiation. The product of this gene has been shown to participate in signaling pathways in response to hormones or cellular stress, and elevated levels of this protein may be associated with breast cancer development.
Synonyms:
protein phosphatase 5, catalytic subunit
NCBI Summary:
This gene encodes a serine/threonine phosphatase which is a member of the protein phosphatase catalytic subunit family. Proteins in this family participate in pathways regulated by reversible phosphorylation at serine and threonine residues; many of these pathways are involved in the regulation of cell growth and differentiation. The product of this gene has been shown to participate in signaling pathways in response to hormones or cellular stress, and elevated levels of this protein may be associated with breast cancer development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2011]