The PPP5C Polyclonal Antibody (PAC017371) is specifically designed for research involving PPP5C, a protein phosphatase enzyme involved in various cellular processes such as cell signaling and cell cycle regulation. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the PPP5C protein, this antibody facilitates the detection and analysis of PPP5C in different cell types, making it an excellent tool for studies in molecular biology and cancer research.
PPP5C is a pivotal player in the regulation of cellular pathways, including the modulation of protein phosphorylation states and the control of gene expression. Its involvement in critical cellular functions makes it a key target for research in understanding diseases such as cancer, neurodegenerative disorders, and metabolic syndromes. Unraveling the role of PPP5C is essential for the development of therapies aimed at targeting specific cellular mechanisms implicated in these pathological conditions.
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO17371(PPP5C Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200).
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: A375 cell, Primary antibody: PACO17371(PPP5C Antibody) at dilution 1/300 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds.
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO17371(PPP5C Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200).
Background:
This gene encodes a serine/threonine phosphatase which is a member of the protein phosphatase catalytic subunit family. Proteins in this family participate in pathways regulated by reversible phosphorylation at serine and threonine residues; many of these pathways are involved in the regulation of cell growth and differentiation. The product of this gene has been shown to participate in signaling pathways in response to hormones or cellular stress, and elevated levels of this protein may be associated with breast cancer development.
Synonyms:
protein phosphatase 5, catalytic subunit
NCBI Summary:
This gene encodes a serine/threonine phosphatase which is a member of the protein phosphatase catalytic subunit family. Proteins in this family participate in pathways regulated by reversible phosphorylation at serine and threonine residues; many of these pathways are involved in the regulation of cell growth and differentiation. The product of this gene has been shown to participate in signaling pathways in response to hormones or cellular stress, and elevated levels of this protein may be associated with breast cancer development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2011]
