The PMPCB Polyclonal Antibody (CAB4312) is specially designed for research involving the PMPCB protein, a cell surface molecule known for its role in mitochondrial protein localization and regulation. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in various applications, including Western blot and immunofluorescence.PMPCB plays a crucial role in maintaining mitochondrial function and cellular metabolism, making it a key player in cellular homeostasis and energy production. Dysregulation of PMPCB has been implicated in a range of diseases, including metabolic disorders, neurodegenerative diseases, and cancer.
By targeting PMPCB in research, scientists can gain valuable insights into the mechanisms underlying these conditions and potentially identify new therapeutic targets.By utilizing the PMPCB Polyclonal Antibody, researchers can effectively detect and analyze PMPCB expression in different cell types, providing important data for studies in mitochondrial biology, metabolism, and disease pathology. This antibody is a valuable tool for advancing our understanding of PMPCB's function and its potential as a therapeutic target in various disease contexts.
Product Name:
PMPCB Rabbit Polyclonal Antibody
SKU:
CAB4312
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 110-380 of human PMPCB (NP_004270.2).
This gene is a member of the peptidase M16 family and encodes a protein with a zinc-binding motif. This protein is located in the mitochondrial matrix and catalyzes the cleavage of the leader peptides of precursor proteins newly imported into the mitochondria, though it only functions as part of a heterodimeric complex.
Purification Method:
Affinity purification
Gene ID:
9512
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PMPCB antibody (CAB4312) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
