The PLA2G4D Polyclonal Antibody (CAB15224) is a crucial tool for researchers studying PLA2G4D, an enzyme involved in the regulation of lipid metabolism and inflammation. This antibody is produced in rabbits and is highly specific to human samples, making it suitable for Western blot applications. By targeting the PLA2G4D protein, this antibody allows for the detection and analysis of PLA2G4D expression in various cell types, making it an essential component for studies focusing on lipid signaling pathways, inflammation, and related diseases.
PLA2G4D, also known as cytosolic phospholipase A2 delta, plays a vital role in lipid signaling cascades that regulate inflammation and immune responses. Dysregulation of PLA2G4D activity has been implicated in various diseases, including cancer, cardiovascular disorders, and neuroinflammatory conditions. By understanding the function of PLA2G4D, researchers can uncover new therapeutic targets for these debilitating diseases and develop potential treatment strategies to modulate lipid metabolism and inflammation.
Product Name:
PLA2G4D Rabbit Polyclonal Antibody
SKU:
CAB15224
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 510-680 of human PLA2G4D (NP_828848.3).
The phospholipase A2 enzyme family, including PLA2G4D, catalyze the hydrolysis of glycerophospholipids at the sn-2 position and then liberate free fatty acids and lysophospholipids (Chiba et al., 2004 [PubMed 14709560]).
Purification Method:
Affinity purification
Gene ID:
283748
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Immunofluorescence analysis of Hela cells using PLA2G4D Rabbit pAb (CAB15224) at dilution of 1:100 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
