PKIG Antibody (PACO11270)
- SKU:
- PACO11270
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
PKIG Antibody (PACO11270)
The PKIG Antibody (PAC011270) is a high-quality polyclonal antibody specifically designed for research involving the PKIG protein. PKIG is a key regulator of protein kinase G, a crucial enzyme involved in various cellular processes such as cell proliferation, differentiation, and apoptosis. This antibody is raised in rabbits and has been validated for its reactivity with human samples, making it suitable for use in Western blot applications. By binding to the PKIG protein, this antibody enables researchers to detect and analyze PKIG expression in a variety of cell types, allowing for further study in areas such as signal transduction, cell cycle regulation, and cancer biology.
The PKIG Antibody is a valuable tool for researchers working in fields such as cell biology, molecular biology, and cancer research. Understanding the function and regulation of PKIG is essential for unraveling its role in various physiological and pathological conditions, making this antibody an indispensable resource for studies aiming to elucidate the complex mechanisms involving PKIG.
| Antibody Name: | PKIG Antibody (PACO11270) |
| Antibody SKU: | PACO11270 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human PKIG |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | protein kinase (cAMP-dependent, catalytic) inhibitor gamma;PKIG;MGC126458;MGC126459 ; |
| UniProt Protein Function: | PKIG: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains. Belongs to the PKI family. |
| UniProt Protein Details: | Protein type:Inhibitor; Protein kinase, regulatory subunit Chromosomal Location of Human Ortholog: 20q12-q13.1 Cellular Component: cytoplasm; nucleus Molecular Function:cAMP-dependent protein kinase inhibitor activity Biological Process: negative regulation of protein import into nucleus; negative regulation of transcription from RNA polymerase II promoter; signal transduction |
| NCBI Summary: | This gene encodes a member of the protein kinase inhibitor family. Studies of a similar protein in mice suggest that this protein acts as a potent competitive cAMP-dependent protein kinase inhibitor, and is a predominant form of inhibitor in various tissues. The encoded protein may be involved in osteogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
| UniProt Code: | Q9Y2B9 |
| NCBI GenInfo Identifier: | 74355324 |
| NCBI Gene ID: | 11142 |
| NCBI Accession: | AAI04257.1 |
| UniProt Related Accession: | Q9Y2B9 |
| Molecular Weight: | 7,910 Da |
| NCBI Full Name: | Protein kinase (cAMP-dependent, catalytic) inhibitor gamma |
| NCBI Synonym Full Names: | protein kinase (cAMP-dependent, catalytic) inhibitor gamma |
| NCBI Official Symbol: | PKIGÂ Â |
| NCBI Official Synonym Symbols: | PKI-gamma  |
| NCBI Protein Information: | cAMP-dependent protein kinase inhibitor gamma |
| UniProt Protein Name: | cAMP-dependent protein kinase inhibitor gamma |
| Protein Family: | cAMP-dependent protein kinase |
| UniProt Gene Name: | PKIGÂ Â |
| UniProt Entry Name: | IPKG_HUMAN |
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