The Phospho-p38 MAPK (T180/Y182) Monoclonal Antibody (CABP1361) is a valuable tool for research involving the phosphorylation of p38 MAPK, a key signaling molecule in cellular responses to stress and inflammation. This antibody, produced through monoclonal antibody technology, is highly specific to the phosphorylated form of p38 MAPK at threonine 180 and tyrosine 182 residues in human samples.With its high specificity and sensitivity, the Phospho-p38 MAPK (T180/Y182) Monoclonal Antibody is ideal for use in Western blot applications, allowing for the detection and quantification of phosphorylated p38 MAPK in various cell types and tissues. This antibody enables researchers to study the activation and regulation of p38 MAPK signaling pathways, providing insights into its role in processes such as inflammation, cell proliferation, and apoptosis.
The phosphorylation of p38 MAPK at threonine 180 and tyrosine 182 residues is known to be critical for its activation and downstream signaling effects. By using this antibody to target these specific phosphorylation sites, researchers can gain a better understanding of the molecular mechanisms underlying p38 MAPK signaling and its implications in diseases such as cancer, inflammatory disorders, and neurodegenerative conditions.Overall, the Phospho-p38 MAPK (T180/Y182) Monoclonal Antibody (CABP1361) is a
Product Name:
Phospho-p38 MAPK-T180/Y182 Monoclonal Antibody
SKU:
CABP1361
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic phosphorylated peptide around T180 & Y182 of human Phospho-p38 MAPK-T180/Y182MAPK11 (NP_002742.3).
This gene encodes a member of a family of protein kinases that are involved in the integration of biochemical signals for a wide variety of cellular processes, including cell proliferation, differentiation, transcriptional regulation, and development. The encoded protein can be activated by proinflammatory cytokines and environmental stresses through phosphorylation by mitogen activated protein kinase kinases (MKKs). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
Purification Method:
Affinity purification
Gene ID:
5600/6300/5603/1432
Clone Number:
ARC51023
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using Phospho-p38 MAPK-T180/Y182 Rabbit mAb (CABP1361) at 1:20000 dilution.293T and NIH/3T3 cells were treated by UV at room temperature for 15-30 minutes.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
