Phospho-ERK1-T202 + ERK2-T185 Rabbit Monoclonal Antibody (CABP0485)
- SKU:
- CABP0485
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | Phospho-ERK1-T202 + ERK2-T185 Rabbit Monoclonal Antibody |
SKU: | CABP0485 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic phosphorylated peptide around T202 of human ERK1 (P27361). |
Sequence: | FLTE Y |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | H3.4; H3/g; H3FT; H3t; H3/A; H3FA; ERK1 / ERK2; Phospho-ERK1-T202 + ERK2-T185 |
Positive Sample: | Jurkat+PMA/TPA,NIH/3T3+PMA/TPA |
Conjugate: | Unconjugated |
Cellular Localization: | caveola, cytoplasm, cytoskeleton, cytosol, early endosome, endoplasmic reticulum lumen, extracellular region, focal adhesion, Golgi apparatus, late endosome, microtubule organizing center, mitochondrion, mitotic spindle, nucleoplasm, nucleus, plasma membrane |
Calculated MW: | 42,44kDa |
Observed MW: | 42kDa/44kDa |
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.
Purification Method: | Affinity purification |
Gene ID: | 5594/5595 |
Clone Number: | ARC0100 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |