The Phospholipase D2 Polyclonal Antibody (PAC048678) is a valuable tool for researchers studying the role of Phospholipase D2 (PLD2) in cellular processes. PLD2 is an enzyme involved in lipid metabolism and signaling pathways, making it a crucial player in cell growth, differentiation, and intracellular vesicle trafficking.This antibody, produced in rabbits, is highly specific for detecting PLD2 in human samples and is validated for use in Western blot applications. By targeting PLD2, researchers can study its functions in various cell types and gain insights into its implications in diseases such as cancer, neurodegenerative disorders, and cardiovascular diseases.
Understanding the mechanisms by which PLD2 operates is key to developing targeted therapies that can manipulate its activity for therapeutic purposes. The PAC048678 antibody provides a reliable tool for investigating the role of PLD2 in physiological and pathological conditions, advancing research in biochemistry, cell biology, and drug development.
Western Blot. Positive WB detected in: Mouse liver tissue. All lanes: PHLDB2 antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 143, 137, 140 kDa. Observed band size: 143, 96 kDa..
Immunohistochemistry of paraffin-embedded human gastric cancer using PACO48678 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human adrenal gland tissue using PACO48678 at dilution of 1:100.
Background:
Seems to be involved in the assembly of the postsynaptic apparatus. May play a role in acetyl-choline receptor (AChR) aggregation in the postsynaptic membrane (By similarity).
Synonyms:
Pleckstrin homology-like domain family B member 2 (Protein LL5-beta), PHLDB2, LL5B
UniProt Protein Function:
Seems to be involved in the assembly of the postsynaptic apparatus. May play a role in acetyl-choline receptor (AChR) aggregation in the postsynaptic membrane ().
