The PGK2 Polyclonal Antibody (CAB12952) is a valuable tool for researchers studying PGK2, a key enzyme involved in glycolysis and ATP generation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the PGK2 protein, this antibody enables specific detection and analysis in a variety of cell types, making it an ideal choice for studies in biochemistry, metabolism, and cancer research.PGK2, also known as phosphoglycerate kinase 2, plays a crucial role in the energy production pathways of cells, making it essential for cellular metabolism and function. Its involvement in glycolysis and ATP production highlights its importance in processes such as cell growth, proliferation, and survival.
Given its significance in cellular energy metabolism, PGK2 is a promising target for research aimed at understanding metabolic disorders, cancer, and other diseases related to energy imbalance.Overall, the PGK2 Polyclonal Antibody (CAB12952) provides researchers with a reliable tool for investigating the role of PGK2 in cellular metabolism and its potential implications for various disease states. By studying PGK2 activity and regulation, researchers may gain valuable insights into metabolic pathways and develop novel therapeutic strategies targeting metabolic dysregulation in diseases like cancer and metabolic disorders.
Product Name:
PGK2 Rabbit Polyclonal Antibody
SKU:
CAB12952
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 242-360 of human PGK2 (NP_620061.2).
This gene is intronless, arose via retrotransposition of the phosphoglycerate kinase 1 gene, and is expressed specifically in the testis. Initially assumed to be a pseudogene, the encoded protein is actually a functional phosphoglycerate kinase that catalyzes the reversible conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate, during the Embden-Meyerhof-Parnas pathway of glycolysis, in the later stages of spermatogenesis.
Purification Method:
Affinity purification
Gene ID:
5232
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PGK2 Rabbit pAb (CAB12952) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
