PEX3 Rabbit Polyclonal Antibody (CAB7352)
- SKU:
- CAB7352
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Description
Product Name: | PEX3 Rabbit Polyclonal Antibody |
SKU: | CAB7352 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 144-373 of human PEX3 (NP_003621.1). |
Sequence: | NAAV GKNG TTIL APPD VQQQ YLSS IQHL LGDG LTEL ITVI KQAV QKVL GSVS LKHS LSLL DLEQ KLKE IRNL VEQH KSSS WINK DGSK PLLC HYMM PDEE TPLA VQAC GLSP RDIT TIKL LNET RDML ESPD FSTV LNTC LNRG FSRL LDNM AEFF RPTE QDLQ HGNS MNSL SSVS LPLA KIIP IVNG QIHS VCSE TPSH FVQD LLTM EQVK DFAA NVYE AFST PQQL EK |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | TRG18; PBD10A; PBD10B; PEX3 |
Positive Sample: | Jurkat,Rat liver,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Multi-pass membrane protein, Peroxisome membrane. |
Calculated MW: | 42kDa |
Observed MW: | 37kDa |
The product of this gene is involved in peroxisome biosynthesis and integrity. It assembles membrane vesicles before the matrix proteins are translocated. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause Zellweger syndrome (ZWS).
Purification Method: | Affinity purification |
Gene ID: | 8504 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |