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PerCP/Cyanine5.5 Anti-Mouse Ly6A/E (Sca-1) Antibody [D7] (AGEL2357)

SKU:
AGEL2357
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, κ
Clone:
D7
Conjugation:
PerCP/Cyanine5.5
$263 - $695
Frequently bought together:

Description

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PerCP/Cyanine5.5 Anti-Mouse Ly6A/E (Sca-1) Antibody [D7]

The PercP-Cyanine5.5 Anti-Mouse Ly6A/E (Sca-1) Antibody (D7) is a high-quality research tool designed for the detection and analysis of Ly6A/E (Sca-1) expression in mouse samples. This monoclonal antibody, clone D7, is specifically engineered for flow cytometry applications and is highly reactive with the Ly6A/E (Sca-1) protein.Ly6A/E (Sca-1) is a cell surface antigen commonly used as a marker for stem cells and progenitor cells in mice. The expression of Ly6A/E (Sca-1) is indicative of stem cell populations and is crucial for the identification and characterization of specific cell types in research fields such as stem cell biology, developmental biology, and immunology.The D7 Antibody provides researchers with a reliable tool for studying the expression patterns and dynamics of Ly6A/E (Sca-1) in mouse samples, allowing for detailed investigations into stem cell populations and cellular heterogeneity.

Its specificity and sensitivity make it an essential component for flow cytometry assays aimed at understanding the role of Ly6A/E (Sca-1) in various biological processes, including tissue regeneration, immune cell differentiation, and disease pathogenesis.By utilizing the PercP-Cyanine5.5 Anti-Mouse Ly6A/E (Sca-1) Antibody (D7), researchers can enhance their experimental capabilities and gain valuable insights into the intricate mechanisms governing stem cell biology and immune function in mouse models.

Product Title:PerCP/Cyanine5.5 Anti-Mouse Ly6A/E (Sca-1) Antibody [D7]
SKU:AGEL2357
Size:25µg, 100µg
Clone No:D7
Synonyms:Ly6a;Ly6;Ly-6A.2/Ly-6E.1;SCA-1;TAP;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PerCP/Cyanine5.5 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PerCP/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P05533
Gene ID:110454
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:Ly-6A/E, also known as Sca-1, is an 18 kD member of the Ly-6 multigene family. Ly6A/E is a glycosylphosphatidylinositol (GPI)-linked protein expressed on hematopoietic stem cells. In mice expressing the Ly-6.2 haplotype (e.g., AKR, C57BL, C57BR, DBA/2, SJL, SWR, and 129), Ly-6A/E is also expressed on peripheral B lymphocytes and thymic and peripheral T lymphocytes. Strains expressing the Ly-6.1 haplotype (e.g., BALB/c, CBA, C3H/He, DBA/1, and NZB) have low Ly-6A/E expression on resting peripheral lymphocytes. The expression of Ly-6A/E on lymphocytes is upregulated upon activation from both Ly6.1 and Ly6.2 haplotype mice. Ly-6A/E is thought to be involved in the regulation of both T and B cell responses.

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