The PerCP-Cyanine5.5 Anti-Human CD24 Antibody (ML5) from AssayGenie is a potent tool for researchers studying the CD24 cell surface molecule. This antibody is specifically designed for human samples and is validated for flow cytometry applications. By targeting the CD24 protein, this antibody enables precise detection and analysis in various cell populations, making it an excellent choice for investigations in immunology, oncology, and stem cell research.CD24 is a glycosylphosphatidylinositol-anchored cell adhesion molecule that is involved in various cellular processes, including cell proliferation, differentiation, and migration. Its overexpression has been associated with tumorigenesis and metastasis in multiple cancer types, making it a promising target for cancer research and therapy development.
Additionally, CD24 plays a role in immune response modulation and may be implicated in autoimmune diseases and inflammatory conditions.By utilizing the PerCP-Cyanine5.5 Anti-Human CD24 Antibody (ML5), researchers can gain valuable insights into the function and expression of CD24 in different cell types, paving the way for advancements in understanding disease mechanisms and exploring targeted treatment strategies. This antibody is a reliable tool for high-quality flow cytometry studies, offering precise and specific detection of CD24 expression levels in human samples.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P25063
Gene ID:
100133941
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD24 is a 35-45 kD glycosylphosphatidylinositol (GPI)-linked protein also known as heat stable antigen (HSA), BA-1, Ly-52, and nectadrin. It is expressed on the surface of B cells (but not plasma cells), granulocytes, follicular dendritic cells, and epithelial cells. CD24 may play a role in the regulation of B-cell proliferation and maturation. CD24 crosslinking induces a Ca2+ flux in mature B cells. CD24 has been shown to interact with CD62P (P-selectin).