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PerCP/Cyanine5.5 Anti-Human CD16 Antibody [3G8] (AGEL2481)

SKU:
AGEL2481
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG1, κ
Clone:
3G8
Conjugation:
PerCP/Cyanine5.5
€259 - €889
Frequently bought together:

Description

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PerCP/Cyanine5.5 Anti-Human CD16 Antibody [3G8]

The PerCP-Cyanine5.5 Anti-Human CD16 Antibody (3G8) offered by Assay Genie is a powerful tool for researchers studying the CD16 protein in human samples. This monoclonal antibody is specifically designed to target CD16, a crucial cell surface molecule involved in immune responses. The 3G8 antibody is highly reactive and provides accurate and reliable results in flow cytometry and fluorescence-activated cell sorting (FACS) applications.CD16, also known as FcγRIII, plays a significant role in immune cell activation and antibody-dependent cellular cytotoxicity (ADCC).

By targeting this protein with the 3G8 antibody, researchers can analyze and quantify CD16 expression in various cell types, allowing for in-depth investigation of immune responses, particularly in the context of infectious diseases, autoimmune disorders, and cancer immunotherapy.With its high specificity and sensitivity, the PerCP-Cyanine5.5 Anti-Human CD16 Antibody (3G8) from Assay Genie is an essential tool for scientists seeking to understand the complex mechanisms of immune regulation and develop novel therapeutic strategies targeting the CD16 pathway.

Product Title:PerCP/Cyanine5.5 Anti-Human CD16 Antibody [3G8]
SKU:AGEL2481
Size:20 Tests, 100 Tests, 200 Tests
Clone No:3G8
Synonyms:FcγRIII;Fc gamma receptor;Fc gamma receptor 3;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PerCP/Cyanine5.5 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PerCP/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P08637 O75015
Gene ID:941
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD16 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD16 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD16 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD16 appears to be expressed later in the immune response than CD86. CD16 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

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