The PE-GenieFluor 594 Anti-Mouse CD4 Antibody (GK1.5) is a powerful tool for researchers studying CD4, a critical cell surface marker that plays a key role in immune response regulation. This antibody, specifically designed for use in mouse samples, is produced using the highest quality materials and has been rigorously validated for use in flow cytometry applications. By specifically binding to CD4, this antibody enables accurate and reliable detection and analysis of CD4-expressing cells in various experimental settings, making it an indispensable tool for immunology and research studies.CD4, a glycoprotein found on the surface of helper T cells, is essential for coordinating immune responses and facilitating communication between different immune cell types.
Its role in modulating immune function and orchestrating the body's defense mechanisms makes it a pivotal target for investigations into infectious diseases, autoimmune conditions, and immunotherapy development. Researchers can leverage the specificity and sensitivity of the PE-GenieFluor 594 Anti-Mouse CD4 Antibody (GK1.5) to gain insights into the function and behavior of CD4-positive cells, ultimately advancing our understanding of immune system dynamics and potential therapeutic strategies.
PE/Genie Fluor 594 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
PE/Genie Fluor594
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P06332
Gene ID:
12504
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD4 is a 55 kD protein also known as L3T4 or T4. It is a member of the Ig superfamily, primarily expressed on most thymocytes, a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a coreceptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosin kinase, lck.