The PE-Cyanine7 Anti-Mouse CD38 Antibody (NIMR5) is a potent tool for researchers studying CD38, a cell surface protein known for its roles in immune cell function, inflammation, and signal transduction. This antibody, developed and validated for use in flow cytometry and immunofluorescence applications, specifically targets the mouse CD38 antigen for accurate detection and analysis in various experimental settings.CD38 is a multifunctional enzyme involved in immune responses, cell adhesion, and calcium signaling pathways, making it a key player in immunology and cancer research. The PE-Cyanine7 Anti-Mouse CD38 Antibody (NIMR5) allows for precise visualization and quantification of CD38-expressing cells, facilitating the investigation of immune cell activation, differentiation, and regulatory mechanisms.
By leveraging the specificity and high reactivity of this antibody, researchers can explore the intricate functions of CD38 in immune modulation, inflammatory diseases, and potential therapeutic interventions. The PE-Cyanine7 Anti-Mouse CD38 Antibody (NIMR5) empowers studies aimed at unraveling the complexities of immune system regulation and advancing our understanding of CD38-related pathologies.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P56528
Gene ID:
12494
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD38 is a 42 kD glycoprotein, also known as T10. It is an ADP-ribosyl hydrolase, expressed on B cells, NK cells, a subset of T cells, brain, muscle, and kidney. In mouse, CD38 expression is downregulated on germinal center B cells and plasma cells, whereas this is not the case for humans. By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, as well as adhesion and metabolism of cADPR and NAADP. CD31 is the ligand of CD38.