The PE-Cyanine5 Anti-Human CD34 Antibody (4H11) is a powerful tool designed for the specific detection and analysis of CD34, a well-known marker of hematopoietic stem and progenitor cells. This antibody, meticulously produced for high reactivity and precision, is ideal for research applications in immunology, hematology, and stem cell biology.CD34 is a key cell surface antigen widely used in the identification and isolation of hematopoietic stem cells, with vital implications in both basic research and clinical applications. The unique binding properties of the PE-Cyanine5 Anti-Human CD34 Antibody (4H11) enable robust detection of CD34 expression, facilitating accurate characterization and sorting of stem and progenitor cell populations.
By targeting CD34 with exceptional specificity, this antibody empowers researchers to explore the roles of hematopoietic stem cells in development, regeneration, and disease. Its reliability and performance make it an indispensable tool for studies involving hematopoiesis, leukemia, and cellular therapy, contributing valuable insights to scientific investigations and potential therapeutic interventions.
Product Title:
PE/Cyanine5 Anti-Human CD34 Antibody [4H11]
SKU:
AGEL3440
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
4H11
Synonyms:
Gp105-120; My10;
Host Species:
Mouse
Reactivity:
Human
Application:
FCM
Isotype:
Mouse IgG1, κ
Form:
Liquid
Conjugation:
PE/Cyanine 5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P28906
Gene ID:
947
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD34, also known as gp105-120, is a type I monomeric sialomucin-like glycophosphoprotein with an approximate molecular weight of 105-120 kD. Selectively expressed on the majority of hematopoietic stem/progenitor cells, bone marrow stromal cells, capillary endothelial cells, embryonic fibroblasts, and some nervous tissue, CD34 is a commonly used marker to identify human hematopoietic stem/progenitor cells. According to the differential sensitivity to enzymatic cleavage, four groups of epitopes of CD34 have been described. CD34 mediates cell adhesion and lymphocytes homing through binding to L-selectin and E-selectin ligands.