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PE Anti-Mouse Fc?RI? Antibody [MAR-1] (AGEL2315)

SKU:
AGEL2315
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Armenian Hamster
Isotype:
Armenian Hamster IgG
Clone:
MAR-1
Conjugation:
PE
€129 - €259
Frequently bought together:

Description

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PE Anti-Mouse FcεRIα Antibody [MAR-1]

The MAR-1 PE Anti-Mouse Fc RI Antibody is a vital tool for research involving Fc receptors, key players in the immune response. This antibody, specifically designed for use with mouse samples, is raised in rabbits and validated for flow cytometry applications. By targeting the Fc RI protein, it enables precise detection and analysis of Fc receptor expression in various cell populations, making it an essential component for studies in immunology and antibody-mediated immune responses.Fc receptors are crucial in mediating the effects of antibodies and play a central role in the immune system's defense mechanisms.

The ability to accurately assess Fc receptor expression is essential for understanding how these receptors influence immune cell activation and function. Researchers studying aspects of host defense, antibody-mediated immunity, and autoimmune disorders will find the MAR-1 PE Anti-Mouse Fc RI Antibody to be a valuable resource in their experiments.Discover new insights into immune regulation and antibody-dependent processes with the MAR-1 PE Anti-Mouse Fc RI Antibody, providing a reliable and specific tool for flow cytometry analysis in mouse models.

Product Title:PE Anti-Mouse FcεRIα Antibody [MAR-1]
SKU:AGEL2315
Size:50 Tests, 100 Tests, 200 Tests
Clone No:MAR-1
Synonyms:High affinity immunoglobulin epsilon receptor subunit alpha;Fc-epsilon RI-alpha;FcERI;Fcer1a;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:PE Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P20489
Gene ID:14125
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:FcεRIα is a transmembrane protein belonging to the Ig superfamily. FcεRIα forms a tetrameric complex with one β and two γ-subunits. The FcεRI complex plays an important role in triggering IgE-mediated allergic reactions. It is abundantly expressed on mast and basophils and up-regulated by the presence of IgE. Following stimulation via FcεRIα, mast cells and basophils release bioactive chemical mediators such as histamine, resulting in the initiation of allergic reactions. Cross linking of the high-affinity receptor for IgE on tissue mast cells triggers immediate hypersensitivity with local symptoms. The MAR-1 monoclonal antibody reacts with the FcεRIα subunit.

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