The PE Anti-Human CD31 Antibody (Clone 158-2B3) offered by Assay Genie is a potent tool for researchers studying CD31, a key cell surface marker involved in vascular biology and immune response regulation. This antibody, conjugated to phycoerythrin (PE), exhibits high specificity and sensitivity in detecting human CD31 in flow cytometry and immunofluorescence applications.CD31, also known as platelet endothelial cell adhesion molecule (PECAM-1), plays a crucial role in various cellular processes, including leukocyte migration, endothelial cell adhesion, and signal transduction. By targeting CD31, researchers can gain insights into the function and behavior of endothelial cells, immune cells, and vascular structures in both normal physiology and disease settings.
The PE Anti-Human CD31 Antibody (Clone 158-2B3) offers researchers a reliable tool for investigating angiogenesis, inflammation, vascular integrity, and immune cell interactions. Its validated performance in flow cytometry ensures accurate and reproducible results, making it an indispensable reagent for experiments aimed at deciphering the intricate mechanisms underlying vascular biology and immune response modulation.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P16284
Gene ID:
5175
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD31 is a 130-140 kD type I transmembrane glycoprotein also known as platelet endothelial cell adhesion molecule-1 (PECAM-1) or Endocam. It is expressed on monocytes, platelets, granulocytes, endothelial cells and lymphocyte subsets. CD31 has been reported to bind CD38 and be involved in wound healing, angiogenesis, and cellular migration in an inflammatory situation.