NRF1 Rabbit Polyclonal Antibody (CAB5547)
- SKU:
- CAB5547
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | NRF1 Rabbit Polyclonal Antibody |
SKU: | CAB5547 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 240-449 of human NRF1 (NP_001035199.1). |
Sequence: | WANV RSDV RTEE QKQR VSWT QALR TIVK NCYK QHGR EDLL YAFE DQQT QTQA TATH SIAH LVPS QTVV QTFS NPDG TVSL IQVG TGAT VATL ADAS ELPT TVTV AQVN YSAV ADGE VEQN WATL QGGE MTIQ TTQA SEAT QAVA SLAE AAVA ASQE MQQG ATVT MALN SEAA AHAV ATLA EATL QGGG QIVL SGET AAAV GALT GVQD AN |
Tested Applications: | WB ChIP ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 ChIP,5μg antibody for 10μg-15μg of Chromatin |
Synonyms: | ALPHA-PAL; NRF1 |
Positive Sample: | HepG2,PC-3,Mouse brain,Mouse heart,Rat brain,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 54kDa |
Observed MW: | 70kDa |
This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternative splicing results in multiple transcript variants. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for "nuclear factor (erythroid-derived 2)-like 1" which has an official symbol of NFE2L1.
Purification Method: | Affinity purification |
Gene ID: | 4899 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |