The Nrbp2 Polyclonal Antibody (PAC041422) is a crucial tool for researchers studying the Nrbp2 protein, involved in various cellular processes such as DNA repair and cell cycle regulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to Nrbp2, this antibody enables accurate detection and analysis of the protein in different cell types, making it ideal for studies in molecular biology and cancer research.Nrbp2, also known as Nuclear receptor-binding protein 2, is essential for maintaining genomic stability and proper cell division.
Dysregulation of Nrbp2 has been linked to tumorigenesis and other diseases, highlighting its importance in cellular function. Research into the mechanisms of Nrbp2 can provide valuable insights into cancer development and potential therapeutic targets. This antibody's ability to detect Nrbp2 will facilitate further studies into the protein's role in disease progression and treatment strategies.
Immunohistochemistry of paraffin-embedded human endometrial cancer using PACO41422 at dilution of 1:100.
Immunofluorescence staining of Hela cells with PACO41422 at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Immunohistochemistry of paraffin-embedded human adrenal gland tissue using PACO41422 at dilution of 1:100.
Background:
May regulate apoptosis of neural progenitor cells during their differentiation.
Synonyms:
Nuclear receptor-binding protein 2 (Transformation-related gene 16 protein) (TRG-16), NRBP2
