The NOSIP Polyclonal Antibody is a valuable tool for researchers studying NOSIP, a protein involved in regulating nitric oxide synthase (NOS) activity. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is validated for use in Western blot applications. By binding to NOSIP, this antibody enables the detection and analysis of NOSIP in various cell types, making it ideal for studies in molecular biology and cardiovascular research.
NOSIP plays a crucial role in modulating NOS activity, which is essential for numerous physiological processes, including vasodilation and neurotransmission. Dysregulation of NOSIP has been implicated in cardiovascular diseases, neurodegenerative disorders, and inflammation. By understanding the function of NOSIP, researchers can gain insights into the mechanisms underlying these conditions and potentially develop novel therapeutic strategies targeting NOSIP.
Product Name:
NOSIP Polyclonal Antibody
SKU:
CAB21530
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant Protein corresponding to a sequence within amino acids 1-301 of human NOSIP (NP_057037.1).
The protein encoded by this gene may modulate the activity and localization of nitric oxide synthase (endothelial and neuronal) and thus nitric oxide production. Alternative splicing results in multiple transcript variants that encode the same protein.
Purification Method:
Affinity purification
Gene ID:
51070
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and NOSIP knockout (KO) 293T cells using [KO Validated] NOSIP Rabbit pAb (CAB21530) at 1:500 dilution.Secondary antibody:HRP Goat Anti-Rabbit IgG (H+L)(CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
