The NG2/CSPG4 Polyclonal Antibody (CAB22556) is a valuable tool for researchers studying the NG2/CSPG4 protein, an important cell surface marker associated with multiple functions in cellular processes. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for Western blot applications. By specifically targeting the NG2/CSPG4 protein, researchers can accurately detect and analyze its presence in a variety of cell types, making it an ideal tool for studies in cell biology, cancer research, and neuroscience.
NG2/CSPG4, also known as chondroitin sulfate proteoglycan 4, plays a key role in cell adhesion, migration, and proliferation, making it a pivotal molecule in processes such as tissue development and regeneration. Its involvement in cancer progression and neural regeneration highlights its potential as a therapeutic target for various diseases. By delving into the functions of NG2/CSPG4, researchers can uncover novel insights into cell behavior and potentially identify new strategies for treating cancer and neurological disorders.
Enables coreceptor activity. Acts upstream of or within several processes, including platelet-derived growth factor receptor signaling pathway; positive regulation of MAPK cascade; and ruffle assembly. Located in plasma membrane and ruffle. Is expressed in several structures, including brain; jaw; respiratory system; retina; and skeleton. Human ortholog(s) of this gene implicated in relapsing-remitting multiple sclerosis. Orthologous to human CSPG4 (chondroitin sulfate proteoglycan 4).
Purification Method:
Affinity purification
Gene ID:
121021
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using NG2/CSPG4 antibody (CAB22556) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
