NFAT2 Rabbit Monoclonal Antibody (CAB19597)
- SKU:
- CAB19597
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Description
Product Name: | NFAT2 Rabbit Monoclonal Antibody |
SKU: | CAB19597 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 844-943 of human NFAT2 (O95644). |
Sequence: | PSSP SPPL PPAT QEPT CLQP CSPA CPPA TGRP QHLP STVR RDES PTAG PRLL PEVH EDGS PNLA PIPV TVKR EPEE LDQL YLDD VNEI IRND LSST STHS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | NFAT2; NFATc; NF-ATC; NF-ATc1.2 |
Positive Sample: | U-87MG,K-562,Jurkat,293T |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 101kDa |
Observed MW: | 110kDa |
The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.
Purification Method: | Affinity purification |
Gene ID: | 4772 |
Clone Number: | ARC0076 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |