NDUFV1 Rabbit Polyclonal Antibody (CAB8014)
- SKU:
- CAB8014
- Product Type:
- Antibody
- Applications:
- WB
- IF
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | NDUFV1 Rabbit Polyclonal Antibody |
SKU: | CAB8014 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 72-420 of human NDUFV1 (NP_009034.2). |
Sequence: | GPDW ILGE IKTS GLRG RGGA GFPT GLKW SFMN KPSD GRPK YLVV NADE GEPG TCKD REIL RHDP HKLL EGCL VGGR AMGA RAAY IYIR GEFY NEAS NLQV AIRE AYEA GLIG KNAC GSGY DFDV FVVR GAGA YICG EETA LIES IEGK QGKP RLKP PFPA DVGV FGCP TTVA NVET VAVS PTIC RRGG TWFA GFGR ERNS GTKL FNIS GHVN HPCT VEEE MSVP LKEL IEKH AGGV TGGW DNLL AVIP GGSS TPLI PKSV CETV LMDF DALV QAQT GLGT AAVI VMDR STDI VKAI ARLI EFYK HESC GQCT PCRE GVDW MNKV MARF VRGD ARPA EIDS LWEI SKQI E |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IHC-P,1:50 - 1:200 |
Synonyms: | UQOR1; CI-51K; CI51KD; MC1DN4; NDUFV1 |
Positive Sample: | HeLa,HepG2,293T,Mouse heart,Mouse kidney,Rat heart,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Matrix side, Mitochondrion inner membrane, Peripheral membrane protein. |
Calculated MW: | 51kDa |
Observed MW: | 51kDa |
The mitochondrial respiratory chain provides energy to cells via oxidative phosphorylation and consists of four membrane-bound electron-transporting protein complexes (I-IV) and an ATP synthase (complex V). This gene encodes a 51 kDa subunit of the NADH:ubiquinone oxidoreductase complex I; a large complex with at least 45 nuclear and mitochondrial encoded subunits that liberates electrons from NADH and channels them to ubiquinone. This subunit carries the NADH-binding site as well as flavin mononucleotide (FMN)- and Fe-S-biding sites. Defects in complex I are a common cause of mitochondrial dysfunction; a syndrome that occurs in approximately 1 in 10,000 live births. Mitochondrial complex I deficiency is linked to myopathies, encephalomyopathies, and neurodegenerative disorders such as Parkinson's disease and Leigh syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Purification Method: | Affinity purification |
Gene ID: | 4723 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |