The NDUSF4 Monoclonal Antibody is a crucial tool for researchers studying mitochondrial complex I assembly and function. This antibody specifically targets the NDUSF4 protein, a subunit of complex I involved in electron transport and energy production in the mitochondria.Raised in mice, this monoclonal antibody is highly specific and sensitive for detecting NDUSF4 in various experimental settings, such as Western blotting and immunofluorescence. Its reliability and reproducibility make it an essential reagent for exploring the role of NDUSF4 in physiological and pathological conditions.
By using the NDUSF4 Monoclonal Antibody, researchers can gain insights into mitochondrial dysfunction, neurodegenerative diseases, and metabolic disorders linked to defects in complex I assembly. This antibody is a valuable asset for advancing our understanding of mitochondrial biology and developing targeted therapies for related illnesses.
Product Name:
NDUFS4 Monoclonal Antibody
SKU:
CAB22056
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 43-175 of human NDUFS4 (NP_002486.1).
This gene encodes a nuclear-encoded accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I, or NADH:ubiquinone oxidoreductase). Complex I removes electrons from NADH and passes them to the electron acceptor ubiquinone. Mutations in this gene can cause mitochondrial complex I deficiencies such as Leigh syndrome. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
4724
Clone Number:
ARC54574
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using NDUFS4 antibody (CAB22056) at1:20000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
