NAGS Rabbit Polyclonal Antibody (CAB12086)
- SKU:
- CAB12086
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | NAGS Rabbit Polyclonal Antibody |
SKU: | CAB12086 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 295-534 of human NAGS (NP_694551.1). |
Sequence: | NTGG LRDS SHKV LSNV NLPA DLDL VCNA EWVS TKER QQMR LIVD VLSR LPHH SSAV ITAA STLL TELF SNKG SGTL FKNA ERML RVRS LDKL DQGR LVDL VNAS FGKK LRDD YLAS LRPR LHSI YVSE GYNA AAIL TMEP VLGG TPYL DKFV VSSS RQGQ GSGQ MLWE CLRR DLQT LFWR SRVT NPIN PWYF KHSD GSFS NKQW IFFW FGLA DIRD SYEL VNHA KGLP DSFH KPAS DPGS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | AGAS; ARGA; NAGS |
Positive Sample: | 293T,K-562,Mouse liver,Mouse small intestine,Mouse testis,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion matrix. |
Calculated MW: | 58kDa |
Observed MW: | 58kDa |
The N-acetylglutamate synthase gene encodes a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. This gene may regulate ureagenesis by altering NAG availability and, thereby, CPSI activity. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.
Purification Method: | Affinity purification |
Gene ID: | 162417 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |