The MUC13 Monoclonal Antibody (PAC023767) is a powerful tool for studying MUC13, a cell surface glycoprotein that plays a key role in various physiological processes, including cell adhesion and signaling. This antibody, produced using state-of-the-art technology, exhibits high specificity and sensitivity when detecting MUC13 in human samples, making it suitable for a wide range of research applications.MUC13 is known for its involvement in cancer progression, particularly in promoting tumor growth and metastasis. By targeting MUC13 with this monoclonal antibody, researchers can gain valuable insights into the molecular mechanisms underlying cancer development and potentially identify new therapeutic targets for combating this deadly disease.Additionally, MUC13 has been implicated in inflammatory and immune-related disorders, making it an attractive candidate for studies focused on understanding the pathogenesis of conditions such as inflammatory bowel disease and asthma.
With its ability to selectively recognize and bind to MUC13, this antibody is a valuable asset for researchers seeking to unravel the complex interplay between this glycoprotein and various disease states.Overall, the MUC13 Monoclonal Antibody (PAC023767) offers a reliable and accurate means of investigating the functions and implications of MUC13 in both normal physiology and disease, making it an indispensable tool for advancing our knowledge of biological processes and potentially paving the way for novel therapeutic interventions.
Synthesized peptide derived from internal of human MUC13.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from COLO cells, 293 cells and HeLa cells, using MUC13 antibody.
Immunofluorescence analysis of HepG2 cells, using MUC13 antibody.
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using MUC13 antibody.
Background:
Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling.
Synonyms:
Mucin-13 [Precursor]; Down-regulated in colon cancer 1; MUC13; DRCC1; RECC
UniProt Protein Function:
Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling.
NCBI Summary:
Epithelial mucins, such as MUC13, are a family of secreted and cell surface glycoproteins expressed by ductal and glandular epithelial tissues (Williams et al., 2001 [PubMed 11278439]).[supplied by OMIM, Jul 2008]
