The MTG2 Polyclonal Antibody (PACO09642) is a valuable tool for researchers studying the MTG2 protein, a key player in mitochondrial dynamics and function. This antibody, produced in rabbits, exhibits high specificity and sensitivity for human samples, making it an excellent choice for Western blot applications.MTG2 is involved in regulating mitochondrial fusion and fission processes, which are essential for maintaining cellular energy production and overall cell health. Dysregulation of mitochondrial dynamics has been linked to various diseases, including neurodegenerative disorders and metabolic syndromes.
Therefore, studying the role of MTG2 using this antibody can provide crucial insights into potential therapeutic targets for such conditions.With its ability to detect and analyze MTG2 in a variety of cell types, this antibody is well-suited for research in the fields of mitochondrial biology, cellular bioenergetics, and related areas. By understanding the function and regulation of MTG2, researchers can advance their knowledge of mitochondrial dysfunction and its implications for human health.
GTP binding protein 5 (putative);GTPBP5;FLJ10741;MGC29512;ObgH1;dJ1005F21.2 ;
UniProt Protein Function:
MTG2: Involved in the ribosome maturation process. Plays a role of GTPase in vitro. When missing, mitochondria elongation and abnormal nuclear morphology are observed. Belongs to the GTP1/OBG family.Chromosomal Location of Human Ortholog: 20q13.33Cellular Component: mitochondrial inner membrane; mitochondrial matrix; mitochondrial ribosomeMolecular Function: GTPase activity
UniProt Protein Details:
NCBI Summary:
Small G proteins, such as GTPBP5, act as molecular switches that play crucial roles in the regulation of fundamental cellular processes such as protein synthesis, nuclear transport, membrane trafficking, and signal transduction (Hirano et al., 2006 [PubMed 17054726]).[supplied by OMIM, Mar 2008]
