The MTfR1 Polyclonal Antibody (PACO10637) is a valuable tool for researchers interested in studying the MTfR1 protein, which is essential for iron metabolism and transport. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for Western blot applications. By binding to the MTfR1 protein, this antibody enables researchers to detect and analyze MTfR1 expression in a variety of cell types, making it well-suited for studies in the fields of iron biology and metabolism research.
MTfR1 plays a crucial role in the uptake and transport of iron in cells, making it a key player in maintaining iron homeostasis in the body. Dysregulation of MTfR1 function has been linked to iron-related disorders such as anemia and hemochromatosis, as well as certain types of cancer. By studying the expression and function of MTfR1, researchers can gain insight into the mechanisms underlying these diseases and potentially identify new therapeutic targets for their treatment.
May play a role in mitochondrial aerobic respiration. May also regulate mitochondrial organization and fission ().
UniProt Protein Details:
NCBI Summary:
This gene encodes a mitochondrial protein that is characterized by a poly-proline rich region. A chicken homolog of this protein promotes mitochondrial fission and the mouse homolog protects cells from oxidative stress. A related pseudogene of this gene is found on chromosome X. [provided by RefSeq, Mar 2009]
