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PE/Cyanine7 Anti-Mouse CD40 Antibody [FGK4.5/FGK45] (AGEL0777)

SKU:
AGEL0777
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
€259 - €609
Frequently bought together:

Description

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PE/Cyanine7 Anti-Mouse CD40 Antibody [FGK4.5/FGK45]

The Mouse CD40 Monoclonal Antibody (PE-Cyanine7 Conjugated) FGK4.5 (FGK45) (AGEL0777) offered by Assay Genie is a cutting-edge tool for researchers studying the CD40 protein in mice. The antibody, specifically designed for flow cytometry applications, provides a high level of sensitivity and specificity in detecting CD40 expression in various cell types.CD40 is a crucial cell surface receptor that plays a vital role in the regulation of the immune system, particularly in the activation of B cells and antigen-presenting cells. The FGK4.5 (FGK45) antibody targets the CD40 protein, allowing researchers to analyze its expression levels and distribution in different immune cell populations.

This capability is essential for gaining insights into the complex mechanisms underlying immune responses, providing valuable information for studies in immunology, vaccine development, and autoimmune diseases.By using the Mouse CD40 Monoclonal Antibody (PE-Cyanine7 Conjugated) FGK4.5 (FGK45) (AGEL0777), researchers can delve deeper into the intricate functions of CD40 and its interactions with other immune molecules, paving the way for innovative discoveries and therapeutic advancements in the field of immunology.

Product Title:PE/Cyanine7 Anti-Mouse CD40 Antibody [FGK4.5/FGK45]
SKU:AGEL0777
Size:50 Tests, 100 Tests, 200 Tests
Clone No:FGK4.5/FGK45
Synonyms:Tumor necrosis factor receptor superfamily member 5;Cd40;B-cell surface antigen CD40;Bp50;CD40L receptor;CD40;Tnfrsf5;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/Cyanine7 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P27512
Gene ID:21939
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.

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