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PE/Cyanine7 Anti-Mouse CD161/NK1.1 Antibody [PK136] (AGEL0489)

SKU:
AGEL0489
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Mouse
Isotype:
IgG2a,k
Clone:
PK136
Conjugation:
PE/Cy7
€189 - €369
Frequently bought together:

Description

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PE/Cyanine7 Anti-Mouse CD161/NK1.1 Antibody [PK136]

The Mouse CD161/NK1.1 Monoclonal Antibody (PE/Cyanine7 Conjugated, clone PK136) is a powerful tool for researchers studying natural killer (NK) cells and their associated markers. This antibody, available from AssayGenie, specifically binds to CD161/NK1.1, a cell surface receptor found on NK cells and subsets of T cells.CD161, also known as NK1.1 in mice, is a marker associated with NK cell activation and function. Its expression is commonly used to identify and study NK cells in immune responses, making this antibody an essential reagent in immunology research. The PE/Cyanine7 conjugation provides fluorescent detection capabilities for flow cytometry analysis, allowing for the precise identification and characterization of CD161-expressing cells.

By targeting CD161/NK1.1, researchers can further investigate the role of NK cells in immune responses, infectious diseases, and cancer immunology. This monoclonal antibody offers high specificity and sensitivity, enabling reliable detection of CD161/NK1.1 in various experimental settings. Incorporate the Mouse CD161/NK1.1 Monoclonal Antibody (PE/Cyanine7 Conjugated, clone PK136) into your studies to gain insights into NK cell biology and immune regulation.

Product Title:PE/Cyanine7 Anti-Mouse CD161/NK1.1 Antibody [PK136]
SKU:AGEL0489
Size:25µg, 100µg
Clone No:PK136
Synonyms:Killer cell lectin-like receptor subfamily B member 1C;Klrb1c;CD161 antigen-like family member C;Ly-55c;CD161/NK1.1;NKR-P1.9;NKR-P1C;NKR-P1 40;CD161c;
Host Species:Mouse
Reactivity:Mouse
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:PE/Cyanine7 Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P27814 P27812 Q99JB4
Gene ID:17059
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.

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