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PE/Cyanine7 Anti-Mouse CD127/IL-7RA Antibody [A7R34] (AGEL0741)

SKU:
AGEL0741
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
€259 - €609
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Description

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PE/Cyanine7 Anti-Mouse CD127/IL-7RA Antibody [A7R34]

The Mouse CD127 (IL-7RA) Monoclonal Antibody (PE-Cyanine7 Conjugated) A7R34 (AGEL0741) from Assay Genie is a high-quality antibody designed for research applications involving CD127, also known as IL-7RA. This monoclonal antibody, conjugated with PE-Cyanine7, is specifically engineered for use in flow cytometry and fluorescence-based experiments to detect and analyze CD127 expression in mouse samples.CD127, a receptor for interleukin-7 (IL-7), plays a crucial role in the development and maintenance of T cells within the immune system. Its expression levels can provide valuable insights into immune cell populations and their functionality in various research settings. The A7R34 antibody is meticulously validated for specificity and sensitivity, ensuring reliable results for immunology studies, particularly in T cell biology, lymphocyte development, and immunotherapy research.

By targeting CD127, researchers can explore the mechanisms underlying immune system functioning, including T cell differentiation, survival, and response to various stimuli. With its fluorescence conjugation, the A7R34 antibody facilitates precise identification and quantification of CD127-expressing cells, offering a powerful tool for investigating immune responses, infectious diseases, and immune-related disorders in preclinical and translational research.Overall, the Mouse CD127 (IL-7RA) Monoclonal Antibody (PE-Cyanine7 Conjugated) A7R34 (AGEL0741) is a valuable resource for scientists seeking to deepen their understanding of immune cell biology and advance knowledge in immunological research areas.

Product Title:PE/Cyanine7 Anti-Mouse CD127/IL-7RA Antibody [A7R34]
SKU:AGEL0741
Size:50 Tests, 100 Tests, 200 Tests
Clone No:A7R34
Synonyms:Interleukin-7 receptor subunit alpha;Il7r;IL-7 receptor subunit alpha;IL-7R subunit alpha;IL-7R-alpha;IL-7RA;CD127;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/Cyanine7 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P16872
Gene ID:16197
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be an useful marker for identifying memory and effector T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cells proliferation and development.

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