The Mouse CD11a Monoclonal Antibody (PE/Cyanine7 Conjugated) (FD441.8) is a specialized research tool from Assay Genie designed for the detection and analysis of CD11a, a crucial cell surface marker involved in immune cell adhesion and activation. This antibody is specifically tailored for use in flow cytometry applications, offering high sensitivity and specificity in identifying CD11a-positive cells in samples.CD11a, also known as integrin alpha L, is a key component of the LFA-1 (lymphocyte function-associated antigen-1) complex, which plays a vital role in immune responses by mediating cell-cell interactions and signal transduction processes. By targeting CD11a, researchers can gain insights into immune cell function, particularly in processes such as leukocyte trafficking, immune surveillance, and antigen presentation.The Mouse CD11a Monoclonal Antibody (PE/Cyanine7 Conjugated) (FD441.
8) is a reliable tool for immunology and cell biology studies, providing researchers with a means to investigate the expression and activation status of CD11a in various cell populations. With its conjugation to PE/Cyanine7, this antibody offers multiplexing capabilities and compatibility with other fluorescent markers, enhancing its utility in complex experimental setups.Unlock the potential of your research by leveraging the precision and specificity of the Mouse CD11a Monoclonal Antibody (PE/Cyanine7 Conjugated) (FD441.8) from Assay Genie. Explore the intricate world of immune cell interactions and functions with this advanced tool, making significant strides in understanding immune responses and developing targeted therapies for immune-related disorders.
Product Title:
PE/Cyanine7 Anti-Mouse CD11a Antibody [FD441.8]
SKU:
AGEL0827
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
FD441.8
Synonyms:
Integrin alpha-L;Itgal;CD11 antigen-like family member A;LFA-1A;Lymphocyte antigen 15;Ly-15;CD11a;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2b, κ
Isotype Control:
PE/Cyanine7 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
PE/Cyanine 7
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P24063
Gene ID:
16408
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD11a is a 180 kD glycoprotein, also known as αL integrin, LFA-1 α, Ly-15, or Ly-21. It is a member of the integrin family, primarily expressed on lymphocytes, monocytes/macrophages, and granulocytes. In association with CD18, the CD11a/CD18 complex forms LFA-1. CD11a plays an important role in intercellular adhesion and costimulation by binding its ligands, ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).