The MORC1 Polyclonal Antibody (PAC010546) is a valuable tool for researchers studying the MORC1 protein, which plays a key role in epigenetic regulation and chromatin remodeling. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the MORC1 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential tool for studies in molecular biology and cancer research.MORC1 is a member of the MORC family of proteins, known for their involvement in gene silencing and chromatin remodeling processes. The protein's function in epigenetic regulation highlights its significance in controlling gene expression and cellular processes.
Research on MORC1 is particularly relevant for understanding the mechanisms underlying cancer development, as dysregulation of epigenetic processes is a common feature in many types of cancer.Overall, the MORC1 Polyclonal Antibody offers investigators a reliable tool for investigating the role of MORC1 in gene regulation and chromatin dynamics. Its high specificity and sensitivity make it well-suited for a wide range of research applications, providing valuable insights into the molecular pathways involved in cancer and other diseases.
MORC family CW-type zinc finger 1;MORC1;CT33;MORC;ZCW6 ;
UniProt Protein Function:
MORC1: Required for spermatogenesis.Protein type: Oxidoreductase; Cancer Testis Antigen (CTA)Chromosomal Location of Human Ortholog: 3q13
UniProt Protein Details:
NCBI Summary:
This gene encodes the human homolog of mouse morc and like the mouse protein it is testis-specific. Mouse studies support a testis-specific function since only male knockout mice are infertile; infertility is the only apparent defect. These studies further support a role for this protein early in spermatogenesis, possibly by affecting entry into apoptosis because testis from knockout mice show greatly increased numbers of apoptotic cells. [provided by RefSeq, Jan 2009]
