The MINPP1 Polyclonal Antibody (PACO28250) is a valuable tool for researchers studying MINPP1, a phosphatase enzyme involved in cellular processes such as metabolism and signal transduction. This antibody, generated in rabbits, exhibits high specificity for human samples and has been validated for use in Western blot applications. By targeting the MINPP1 protein, this antibody allows for the detection and analysis of MINPP1 expression in various cell types, making it suitable for investigations in metabolic disorders, cancer biology, and signal transduction pathways.
MINPP1 is known for its role in maintaining cellular phosphate homeostasis and has been implicated in diseases such as insulin resistance, diabetes, and neurodegenerative disorders. By studying the function of MINPP1, researchers can gain insights into the mechanisms underlying these conditions and potentially identify novel therapeutic targets. The MINPP1 Polyclonal Antibody is a valuable tool for advancing our understanding of MINPP1 biology and its implications in health and disease.
Antibody Name:
Minpp1 Antibody (PACO28250)
Antibody SKU:
PACO28250
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Rat
Immunogen:
Recombinant Rat Multiple inositol polyphosphate phosphatase 1 protein (31-481AA)
Acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). Also acts as a 2,3-bisphosphoglycerate 3-phosphatase, by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycerate without formation of 3-phosphoglycerate. May play a role in bone development (endochondral ossification).
Acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). Also acts as a 2,3-bisphosphoglycerate 3-phosphatase, by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycerate without formation of 3-phosphoglycerate. May play a role in bone development (endochondral ossification). May play a role in the transition of chondrocytes from proliferation to hypertrophy ().
UniProt Protein Details:
NCBI Summary:
catalyzes the hydrolysis of Ins(1,3,4,5,6)P5, first to Ins(1,4,5,6)P4 and then to Ins(1,4,5)P3, by consecutive 3- and 6-phosphatase activities [RGD, Feb 2006]
