MGP Rabbit Polyclonal Antibody (CAB5439)
- SKU:
- CAB5439
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | MGP Rabbit Polyclonal Antibody |
SKU: | CAB5439 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-103 of human MGP (NP_000891.2). |
Sequence: | YESH ESME SYEL NPFI NRRN ANTF ISPQ QRWR AKVQ ERIR ERSK PVHE LNRE ACDD YRLC ERYA MVYG YNAA YNRY FRKR RGTK |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | NTI; GIG36; MGLAP; MGP |
Positive Sample: | SH-SY5Y |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 12kDa |
Observed MW: | 12kDa |
This gene encodes a member of the osteocalcin/matrix Gla family of proteins. The encoded vitamin K-dependent protein is secreted by chondrocytes and vascular smooth muscle cells, and functions as a physiological inhibitor of ectopic tissue calcification. Carboxylation status of the encoded protein is associated with calcification of the vasculature in human patients with cardiovascular disease and calcification of the synovial membranes in osteoarthritis patients. Mutations in this gene cause Keutel syndrome in human patients, which is characterized by abnormal cartilage calcification, peripheral pulmonary stenosis and facial hypoplasia.
Purification Method: | Affinity purification |
Gene ID: | 4256 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |