The MGAT3 Polyclonal Antibody (CAB8134) is a vital tool for researchers studying MGAT3, a key enzyme involved in the biosynthesis of complex N-glycans. This antibody, produced through rabbit immunization, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the MGAT3 protein, researchers can accurately detect and analyze its expression in various cell types, making it an essential resource for studies in glycobiology and cancer research.MGAT3 plays a crucial role in the maturation and branching of N-glycans, impacting various biological processes such as cell adhesion, signaling, and immune response modulation.
Dysregulation of MGAT3 expression has been linked to cancer progression, autoimmune disorders, and other diseases involving aberrant glycosylation patterns. Investigating the function of MGAT3 can provide valuable insights into disease mechanisms and potential therapeutic targets in the field of glycobiology.In summary, the MGAT3 Polyclonal Antibody (CAB8134) offers researchers a reliable tool to explore the roles of MGAT3 in health and disease, paving the way for advancements in personalized medicine and targeted therapies.
Product Name:
MGAT3 Rabbit Polyclonal Antibody
SKU:
CAB8134
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 364-533 of human MGAT3 (NP_002400.3).
Golgi apparatus membrane, Single-pass type II membrane protein.
Calculated MW:
61kDa
Observed MW:
61kDa
There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. The enzyme encoded by this gene transfers a GlcNAc residue to the beta-linked mannose of the trimannosyl core of N-linked oligosaccharides and produces a bisecting GlcNAc. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Purification Method:
Affinity purification
Gene ID:
4248
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of Mouse kidney, using MGAT3 antibody (CAB8134) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
