The MFAP3L Monoclonal Antibody (PACO16676) is specifically designed for research involving MFAP3L, a protein involved in extracellular matrix remodeling and cell adhesion processes. This antibody is produced using advanced technology and is highly specific to human samples, making it ideal for various research applications.MFAP3L is known to play a crucial role in promoting cell migration and invasion, making it a potential target for studying cancer metastasis and tissue development. The MFAP3L Monoclonal Antibody binds specifically to the MFAP3L protein, enabling researchers to detect and analyze its expression in different cell types.
With its high specificity and sensitivity, researchers can rely on this antibody for studies related to cell biology, cancer research, and extracellular matrix dynamics. By understanding the function of MFAP3L, researchers can gain insights into potential therapeutic strategies for diseases involving abnormal cell migration and tissue remodeling.
Antibody Name:
MFAP3L Antibody (PACO16676)
Antibody SKU:
PACO16676
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:50-1:200
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Fusion protein of human MFAP3L
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO16676(MFAP3L Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200).
Background:
MFAP3L (microfibrillar-associated protein 3-like), also known as HSD39 or testis development protein NYD-SP9, is a 409 amino acid, single-pass type I cell membrane protein that contains one Ig-like (immunoglobulin-like) domain. Found primarily in testis, MFAP3L is encoded by a gene that is located on chromosome 4 and is expressed as three isoforms due to alternative splicing events. Representing approximately 6% of the human genome, chromosome 4 contains nearly 900 genes, one of which is the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease.
Synonyms:
microfibrillar-associated protein 3-like
UniProt Protein Function:
MFAP3L: 3 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 4q32.3Cellular Component: cytoplasm; integral to membrane; nucleus; plasma membraneMolecular Function: protein binding
