The MAGEA10 Monoclonal Antibody (PACO10334) is a valuable tool for studying the MAGEA10 protein, a member of the MAGE protein family that is often associated with cancer. This antibody, produced through hybridoma technology, exhibits high specificity and sensitivity towards MAGEA10 in human samples and is optimized for use in immunofluorescence and immunohistochemistry applications.MAGEA10 is known to be a potential target for cancer therapy due to its involvement in tumor progression and resistance to treatment.
Research on MAGEA10 expression and function can provide insights into the pathogenesis of various types of cancer and facilitate the development of novel treatment strategies.By utilizing the MAGEA10 Monoclonal Antibody (PACO10334), researchers can explore the role of MAGEA10 in oncogenesis, metastasis, and drug resistance, ultimately advancing our understanding of cancer biology and potentially leading to the discovery of new therapeutic interventions.
melanoma antigen family A, 10;MAGEA10;CT1.10;MAGE10;MGC10599 ;
UniProt Protein Function:
MAGE-A10: Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression.Chromosomal Location of Human Ortholog: Xq28Cellular Component: nucleus
UniProt Protein Details:
NCBI Summary:
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Two transcript variants encoding the same protein have been found for this gene. Read-through transcription also exists between this gene and the downstream melanoma antigen family A, 5 (MAGEA5) gene.[provided by RefSeq]
