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MAD1L1 Polyclonal Antibody (CAB24666)

SKU:
CAB24666
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
€129 - €359
Frequently bought together:

Description

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Product Name:MAD1L1 Polyclonal Antibody
SKU:CAB24666
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MAD1L1(NP_003541.2).
Sequence:MEDL GENT MVLS TLRS LNNF ISQR VEGG SGLD ISTS APGS LQMQ YQQS MQLE ERAE QIRS KSHL IQVE REKM QMEL SHKR ARVE LERA ASTS ARNY EREV
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:MAD1; MVA7; PIG9; TP53I9; TXBP181; MAD1L1
Positive Sample:Rat thymus
Conjugate:Unconjugated
Cellular Localization:centrosome, cytoplasm, cytosol, mitotic spindle, mitotic spindle assembly checkpoint MAD1-MAD2 complex, nuclear pore nuclear basket, nucleus, spindle, spindle pole
Calculated MW:83kDa
Observed MW:83kDa

MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Alternative splicing results in multiple transcript variants.

Purification Method:Affinity purification
Gene ID:8379
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from Rat thymus, using MAD1L1 Rabbit pAb (CAB24666) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.

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