The LYPLA1 Polyclonal Antibody (PACO28086) is a research tool specifically designed for studies involving LYPLA1, a key enzyme involved in lipid metabolism and cellular signaling pathways. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the LYPLA1 protein, this antibody enables the detection and analysis of LYPLA1 expression in various cell types, making it an essential tool for research in biochemistry and cell biology.LYPLA1, also known as lysophospholipase 1, plays a crucial role in lipid metabolism by catalyzing the hydrolysis of lysophospholipids. This enzymatic activity is involved in various cellular processes, including cell signaling, membrane remodeling, and lipid homeostasis.
Dysregulation of LYPLA1 has been linked to diseases such as cancer, metabolic disorders, and neurological conditions, highlighting its importance as a potential therapeutic target.By studying the function and regulation of LYPLA1, researchers can gain valuable insights into the mechanisms underlying lipid metabolism and cellular signaling pathways, with implications for the development of novel treatments for diseases associated with dysregulated lipid metabolism. The LYPLA1 Polyclonal Antibody (PACO28086) provides a reliable tool for investigating the role of LYPLA1 in health and disease, ultimately advancing our understanding of lipid metabolism and its impact on human health
Antibody Name:
Lypla1 Antibody (PACO28086)
Antibody SKU:
PACO28086
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Mouse
Immunogen:
Recombinant Mouse Acyl-protein thioesterase 1 protein (1-230AA)
Hydrolyzes fatty acid, from S-acylated cysteine residues in proteins such as trimeric G α proteins or HRAS. Has depalmitoylating activity and also low lysophospholipase activity
LYPLA1: Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has depalmitoylating activity and also low lysophospholipase activity. Belongs to the AB hydrolase 2 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: EC 3.1.2.-; Lipid Metabolism - glycerophospholipid; Mitochondrial; PhospholipaseChromosomal Location of Human Ortholog: 1|1 A1Cellular Component: cytosol; mitochondrionMolecular Function: lipase activity; lysophospholipase activity; palmitoyl-(protein) hydrolase activityBiological Process: negative regulation of Golgi to plasma membrane protein transport; protein depalmitoylation
