LTF Rabbit Polyclonal Antibody (CAB12902)
- SKU:
- CAB12902
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Description
Product Name: | LTF Rabbit Polyclonal Antibody |
SKU: | CAB12902 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-352 of human LTF (NP_002334.2). |
Sequence: | RRRS VQWC AVSQ PEAT KCFQ WQRN MRKV RGPP VSCI KRDS PIQC IQAI AENR ADAV TLDG GFIY EAGL APYK LRPV AAEV YGTE RQPR THYY AVAV VKKG GSFQ LNEL QGLK SCHT GLRR TAGW NVPI GTLR PFLN WTGP PEPI EAAV ARFF SASC VPGA DKGQ FPNL CRLC AGTG ENKC AFSS QEPY FSYS GAFK CLRD GAGD VAFI REST VFED LSDE AERD EYEL LCPD NTRK PVDK FKDC HLAR VPSH AVVA RSVN GKED AIWN LLRQ AQEK FGKD KSPK FQLF GSPS GQKD LLFK DSAI GFSR VPPR IDSG LYLG SGYF TAIQ NLRK |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:100 - 1:200 |
Synonyms: | LF; HLF2; GIG12; HEL110; LTF |
Positive Sample: | Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Cytoplasmic granule, Nucleus, Secreted. |
Calculated MW: | 78kDa |
Observed MW: | 85kDa |
This gene is a member of the transferrin family of genes and its protein product is found in the secondary granules of neutrophils. The protein is a major iron-binding protein in milk and body secretions with an antimicrobial activity, making it an important component of the non-specific immune system. The protein demonstrates a broad spectrum of properties, including regulation of iron homeostasis, host defense against a broad range of microbial infections, anti-inflammatory activity, regulation of cellular growth and differentiation and protection against cancer development and metastasis. Antimicrobial, antiviral, antifungal and antiparasitic activity has been found for this protein and its peptides. Activity against both DNA and RNA viruses has been found, including activity against SARS-CoV-2, and HIV.
Purification Method: | Affinity purification |
Gene ID: | 4057 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |