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LTA Monoclonal Antibody [PAT15A3AT] (CPAB0011)

SKU:
CPAB0011
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2b
Clone:
PAT15A3AT
Applications:
WB
IF
ELISA
€149
Frequently bought together:

Description

system_update_alt Datasheet

LTA Monoclonal Antibody [PAT15A3AT] (CPAB0011)

The LTA Polyclonal Antibody (CPAB0011) is a valuable tool for researchers studying LTA, a key player in the immune response. This antibody, produced in rabbits, is highly specific to human samples and is optimized for use in Western blot applications. By binding to the LTA protein, this antibody allows for the detection and analysis of LTA in a variety of cell types, making it an essential component for studies in immunology and infectious disease research.LTA, also known as lipoteichoic acid, is a cell wall component of gram-positive bacteria that plays a crucial role in the activation of immune responses.

Understanding the function of LTA is important for developing strategies to combat bacterial infections and inflammatory diseases. The LTA Polyclonal Antibody provides researchers with a reliable tool to investigate the role of LTA in immune modulation and identify potential therapeutic targets for treating infections and inflammatory disorders.

Product Name:LTA Antibody
Product Sku:CPAB0011
Size:5μg
Host Species:Mouse
Immunogen:Anti-human LTA mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human LTA amino acids 35-25 purified from Ecoli.
Clone:PAT15A3AT.
Reactivity:Human
Applications:Western Blot, Immunofluorescence, ELISA
Purification Method:LTA antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG2b
Background:Lymphotoxin-alpha (LT-alpha or LTA) belongs to the TNF ligand superfamily, which bind the same TNF receptor and mediate similar pleiotropic effect. LTA is a proinflammatory cytokine with important biological activity and immunomodulatory function and is known to influence a variety of cellular response. Furthermore, LTA mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and has a role in apoptosis. LTA is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchors lymphotoxin-alpha to the cell surface. LTA, which is located within the MHC III region of chromosome 6, shows close relation to the HLA class I (HLA-B) and class II (HLA-DR) genes. Polymorphism in the LTA gene appears to contribute to infectious disease susceptibility and infection. Genetic variations in the LTA gene are linked to susceptibility to leprosy type 4 and psoriatic arthritis.
Synonyms:Lymphotoxin-alpha, LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1, LTA, TNFB, TNFSF1, LT.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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