The LRFN3 Polyclonal Antibody (CAB14927) is a valuable tool for researchers studying LRFN3, a member of the leucine-rich repeat and fibronectin type III domain-containing (LRFN) family of proteins. LRFN3 is involved in synapse formation and function in the brain, making it a key player in neuronal communication and potentially important for neurological disorders.Raised in rabbits, this antibody is highly specific to human samples and has been validated for use in Western blot applications. By binding to the LRFN3 protein, researchers can accurately detect and analyze its expression levels in various cell types, offering insights into its function in synaptic plasticity and neuronal development.
The significance of LRFN3 in brain function and synaptic transmission makes it a promising target for research into neurodevelopmental disorders, cognitive dysfunction, and neurological conditions. By studying LRFN3 with this antibody, researchers can deepen their understanding of its role in the brain and potentially uncover new therapeutic strategies for these disorders.
Product Name:
LRFN3 Rabbit Polyclonal Antibody
SKU:
CAB14927
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 380-530 of human LRFN3 (NP_078785.1).
HT-29,Mouse testis,Mouse small intestine,Rat brain
Conjugate:
Unconjugated
Cellular Localization:
Cell junction, Cell membrane, Cell projection, Single-pass type I membrane protein, axon, dendrite, postsynaptic cell membrane, presynaptic cell membrane, synapse.
Calculated MW:
66kDa
Observed MW:
66kDa
Predicted to be involved in regulation of presynapse assembly; regulation of synaptic membrane adhesion; and synaptic membrane adhesion. Predicted to be located in plasma membrane. Predicted to be active in cell surface and glutamatergic synapse. Predicted to be integral component of postsynaptic density membrane and integral component of presynaptic active zone membrane.
Purification Method:
Affinity purification
Gene ID:
79414
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using LRFN3 Rabbit pAb (CAB14927) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
