The LIPB1 Monoclonal Antibody (PACO22717) is a cutting-edge tool designed for research involving LIPB1, a key protein involved in lipid metabolism and cellular function. This antibody, developed using state-of-the-art technology, specifically targets LIPB1 in human samples and is validated for use in a variety of applications, including immunofluorescence and ELISA.LIPB1, also known as Lipase B1, is a critical enzyme that plays a crucial role in lipid digestion and metabolism. Its involvement in cellular processes makes it a valuable target for studies focused on understanding lipid-related diseases, such as obesity, diabetes, and cardiovascular disorders.
The LIPB1 Monoclonal Antibody provides researchers with a reliable tool to detect and analyze LIPB1 expression in different cell types, offering valuable insights into its functions and regulatory mechanisms.With its high specificity and sensitivity, the LIPB1 Monoclonal Antibody is an essential asset for scientists working in the fields of biochemistry, physiology, and molecular biology. By enabling precise detection and quantification of LIPB1, this antibody facilitates groundbreaking research that aims to unravel the complex intricacies of lipid metabolism and its impact on human health.
Antibody Name:
LIPB1 Antibody (PACO22717)
Antibody SKU:
PACO22717
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from internal of human LIPB1.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from A549 cells, Jurkat cells, HeLa cells, HepG2 cells, COLO205 cells and HuvEc cells, using LIPB1 antibody.
Background:
The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Synonyms:
Liprin-beta-1; Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1; PTPRF-interacting protein-binding protein 1; hSGT2; PPFIBP1
