The LIMCH1 Polyclonal Antibody (CAB17649) is a valuable tool for researchers studying LIM and calponin homology domains-containing protein 1 (LIMCH1). This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the LIMCH1 protein, this antibody enables the detection and analysis of LIMCH1 in various cell types, making it an ideal choice for studies in cell biology and cancer research.
LIMCH1 is a protein involved in actin cytoskeleton dynamics and has been implicated in cell motility, adhesion, and cancer progression. Its role in cytoskeletal organization and cell migration make it a key target for research into cell biology and cancer metastasis. Understanding the function of LIMCH1 is essential for uncovering its potential implications in disease pathogenesis and therapeutic targeting.
Product Name:
LIMCH1 Rabbit Polyclonal Antibody
SKU:
CAB17649
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 150-450 of human LIMCH1 (NP_001106189.1).
Enables myosin II head/neck binding activity. Involved in several processes, including cytoplasmic actin-based contraction involved in cell motility; positive regulation of stress fiber assembly; and regulation of focal adhesion assembly. Located in stress fiber. Colocalizes with myosin II complex.
Purification Method:
Affinity purification
Gene ID:
22998
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from LO2 cells, using LIMCH1 Rabbit pAb (CAB17649) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
