The LHX3 Polyclonal Antibody (CAB17015) is a crucial tool for research involving LHX3, a transcription factor involved in pituitary gland development and hormone regulation. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the LHX3 protein, this antibody enables accurate detection and analysis in various cell types, making it ideal for studies in endocrinology and developmental biology.LHX3 plays a key role in the development and function of the pituitary gland, which is responsible for regulating hormone production in the body.
Dysregulation of LHX3 has been linked to pituitary hormone deficiencies and other endocrine disorders, highlighting the importance of studying this transcription factor in both normal development and disease states. The LHX3 Polyclonal Antibody is a valuable tool for researchers investigating these processes and potential therapeutic interventions in endocrine-related conditions.
Product Name:
LHX3 Rabbit Polyclonal Antibody
SKU:
CAB17015
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human LHX3 (NP_055379.1).
This gene encodes a member of a large family of proteins which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor that is required for pituitary development and motor neuron specification. Mutations in this gene cause combined pituitary hormone deficiency 3. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
8022
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using LHX3 Rabbit pAb (CAB17015) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
