Lamin B2 Rabbit Polyclonal Antibody (CAB6483)
- SKU:
- CAB6483
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Lamin B2 Rabbit Polyclonal Antibody |
SKU: | CAB6483 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 341-620 of human Lamin B2 (NP_116126.3). |
Sequence: | AMAG ERDK FRKM LDAK EQEM TEMR DVMQ QQLA EYQE LLDV KLAL DMEI NAYR KLLE GEEE RLKL SPSP SSRV TVSR ATSS SSGS LSAT GRLG RSKR KRLE VEEP LGSG PSVL GTGT GGSG GFHL AQQA SASG SVSI EEID LEGK FVQL KNNS DKDQ SLGN WRIK RQVL EGEE IAYK FTPK YILR AGQM VTVW AAGA GVAH SPPS TLVW KGQS SWGT GESF RTVL VNAD GEEV AMRT VKKS SVMR ENEN GEEE EEEA EFGE EDLF HQQG DPRT TSRG CYVM |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:100 |
Synonyms: | EPM9; LMN2; LAMB2; MCPH27; Lamin B2 |
Positive Sample: | 293T,HepG2,MCF7,SW620,Mouse liver,Mouse heart |
Conjugate: | Unconjugated |
Cellular Localization: | Lipid-anchor, Nucleoplasmic side, Nucleus inner membrane. |
Calculated MW: | 70kDa |
Observed MW: | 70kDa |
This gene encodes a B type nuclear lamin. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Mutations in this gene are associated with acquired partial lipodystrophy.
Purification Method: | Affinity purification |
Gene ID: | 84823 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |